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A total of 122 of those 166 macula-off patients were operated upon successfully. This success rate of 73.49% is strong contrast to the success rate of 91.63% among trauma patients with their macula in place. Patients with macula-off experienced different outcomes depending on their respective lens status. Of 469 patients with aphakia treated between 1980 and 2001 without trauma as a cause of the retinal detachment, 62.47% suffered a macular detachment. Once again, patients with macula-off had distinctly worse results than those with an unaffected macula (p?<?0.05). In 79.18% of aphakic macula-off patients, the outcome was <a href="http://www.selleck.cn/products/Bleomycin-sulfate.html">Bleomycin</a> considered a success; in aphakic patients with attached macula, the success rate was 86.36%. These differences were less significant in patients with pseudophakia. Of 333 patients with pseudophakia, the macula was affected in 61.56%. Of these 205 patients, 81.95% underwent successful surgery. In 128 patients without macular involvement, the operation was deemed a success in 84.38% (p?<?0.05). Among pseudophakic macula-off patients, the success rates were highest in age groups 61�C70 (87.27%) and 41�C50 (85.00%). The lowest success rates of pseudophakic macula-off patients were registered in the oldest patients, those aged 81�C90 with 75.86%. At the time of their examination at Munster��s University Eye Hospital, 3151 nontrauma patients with retinal detachment still had their natural lens in place. A total of <a href="http://www.selleckchem.com/products/Rapamycin.html">Rapamycin ic50</a> 51.89% of these patients suffered a macular detachment and the macula was intact in 48.05%. The success rate of 88.77% in patients with an intact macula was 8.28% higher than the 80.49% in those with macula-off (p?<?0.01). Almost exactly two-thirds (66.33%) of all our patients with retinal detachment suffered the typical symptoms of this sight-threatening disease, while the remaining 1333 patients did not have any clinical complaints: In the former group, the <a href="http://www.selleckchem.com/products/MG132.html">MG-132 mw</a> success rate of 85.25% was higher than in the asymptomatic patients with an 81.62% success rate. Of the 2623 patients describing symptoms, 1467 (55.93%) suffered a detachment with macula-off. Among those 1333 patients who appeared to be asymptomatic, 667 (50.04%) had their macula detached. This is certainly a surprising result of our analysis: Almost half of these individuals had the most important part of their retina detached without experiencing floaters or flashes or other symptoms associated with retinal detachment. We found not only a statistically significant difference (p?=?0.023) in success rates between symptomatic (89.53%) and asymptomatic (85.99%) patients but also in patients with an affected macula. Patients with macula-off and typical symptoms could be treated successfully 81.87% of the time and asymptomatic patients with macula-off 77.36% (p?=?0.014) of the time. The reason for the higher success rate in the former group might be the fact that patients with symptoms tend to see an ophthalmologist sooner rather than later.
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